Immune System 4th Edition By Parham – Test Bank

Immune System 4th Edition By Parham – Test Bank

THE IMMUNE SYSTEM, FOURTH EDITION

CHAPTER 10: PREVENTING INFECTION AT MUCOSAL SURFACES

© Garland Science 2015

10–1 Explain how secondary lymphoid tissues of the mucosa are (A) similar to and (B) different from secondary lymphoid tissues elsewhere in the body (the systemic immune system).

10–2 Because the mucosae _____, this tissue is predisposed to infection.

1. constitute thin, permeable barriers
2. secrete a continuous layer of mucus
3. generate enzymes and proteoglycans
4. are associated with secretory IgA production
5. are not connected to the lymphatics.

10–3 Identify which of the following is not a property of secreted mucins.

1. contain glycosylated cysteine residues
2. contain many repetitive sequence motifs
3. constitute a viscous matrix stabilized by disulfide bonds
4. bind to positively charged effector molecules
5. encoded by seven genes in humans
6. expressed in different mucosal tissues.

10–4 Unlike secreted mucins, membrane mucins _____.

1. do not trap and kill nearby microorganisms
2. are not cross-linked by disulfide bonds
3. do not possess repetitive domains
4. are not glycosylated
5. are encoded by only one gene in humans.

10–5 Commensal microorganisms in the gastrointestinal tract facilitate all of the following except _____.

1. compete with pathogenic variants for nutrients and space
2. convert toxic substances to benign derivatives
3. degrade plant fibers to make their nutrients available
4. secrete enzymes required for protein degradation
5. synthesize essential metabolites
6. induce the development of gut-associated lymphoid tissue.

10–6 The large population of microbes that contribute to the gut microbiota and have an important role in food processing are called _____.

1. lamina propria
2. Peyer’s patches
3. microfold cells
4. commensal microorganisms
5. opportunists.

10–7 All of the following are part of Waldeyer’s ring except _____.

1. appendix
2. palatine tonsils
3. lingual tonsils
4. adenoids.

10–8 Which of the following pairs is mismatched? (Select all that apply.)

1. appendix: large intestine
2. mesenteric lymph nodes: urogenital tract
3. effector compartment: induction of adaptive immune responses
4. adenoids: base of nose
5. villi: small intestine
6. Peyer’s patches: afferent lymphatics.