Human Genetics Concepts And Applications 11Th Edition By Lewis – Test Bank

Human Genetics Concepts And Applications 11Th Edition By Lewis – Test Bank

Multiple Choice Questions

1. “Epigenetic” means
   A.”inside the gene.”
   B. “inside the protein.”
   C. “outside the gene.”
   D. “outside the protein.”

Bloom’s Level: 02. Understand
Learning Outcome: 11.01 Define epigenetics.
Section: 11.01
Topic: Epigenetics

2. Modifiers of gene expression include
   A.isolated amino acids and tRNAs.
   B. specific classes of proteins and RNA molecules.
   C. specific classes of lipids and carbohydrates.
   D. nicotine and alcohol.

Bloom’s Level: 01. Remember
Learning Outcome: 11.01 Define epigenetics.
Section: 11.01
Topic: Epigenetics

3. Epigenetic changes
   A.pass from one cell generation to the next but do not alter the DNA sequence.
   B. do not pass from one cell generation to the next but do alter the DNA sequence.
   C. irreversibly alter the DNA sequence and are only passed to the next cell generation if they add an advantage.
   D.

alter the RNA codon, which are amino acid assignments of the genetic code.

Bloom’s Level: 02. Understand
Learning Outcome: 11.01 Define epigenetics.
Section: 11.01
Topic: Epigenetics

4. Globin chain switching replaces gamma chains with _____ chains in adult hemoglobin.
   A.epsilon
   B. zeta
   C. beta
   D. alpha

Bloom’s Level: 02. Understand
Learning Outcome: 11.02 Explain how globin chain switching, development of organs, and the types of proteins cells make over time illustrate gene expression.
Section: 11.01
Topic: Epigenetics

Fetal hemoglobin carries _____ percent more oxygen than adult hemoglobin.

5 to 10

20 to 30

50 to 60

80 to 90

Bloom’s Level: 01. Remember
Learning Outcome: 11.02 Explain how globin chain switching, development of organs, and the types of proteins cells make over time illustrate gene expression.
Section: 11.01
Topic: Epigenetics

6. The reason for fetal globin chain switching is that
   A.a fetus has four alpha globin chains and a newborn has four beta globin chains.
   B.

a fetus’s blood is clear until the sixth month and then globin chains turn it red.

1. the newborn needs more iron than the fetus or embryo.
   D.the embryo and fetus receive different concentrations of oxygen compared to after birth.

Bloom’s Level: 02. Understand
Learning Outcome: 11.02 Explain how globin chain switching, development of organs, and the types of proteins cells make over time illustrate gene expression.
Section: 11.01
Topic: Epigenetics

7. Hemoglobin in the embryo consists of
   A.two epsilon chains and two zeta chains.
   B. two gamma chains and two alpha chains.
   C. two gamma chains and two beta chains.
   D. one alpha chain, one beta chain, one epsilon chain, and one gamma chain.

Bloom’s Level: 02. Understand
Learning Outcome: 11.02 Explain how globin chain switching, development of organs, and the types of proteins cells make over time illustrate gene expression.
Section: 11.01
Topic: Epigenetics

8. A treatment for some forms of anemia is to take a drug that turns on transcription of fetal hemoglobin. This would increase the proportion of _____ globin chains.
   A.alpha
   B. gamma
   C. delta
   D. epsilon

Bloom’s Level: 03. Apply
Learning Outcome: 11.02 Explain how globin chain switching, development of organs, and the types of proteins cells make over time illustrate gene expression.
Section: 11.01
Topic: Epigenetics

Fetal hemoglobin is hemoglobin that consists of two gamma chains and _____.

two alpha chains

two beta chains

two zeta chains

two epsilon chains

Bloom’s Level: 01. Remember
Learning Outcome: 11.02 Explain how globin chain switching, development of organs, and the types of proteins cells make over time illustrate gene expression.
Section: 11.01
Topic: Epigenetics

10. Development of the pancreas in an embryo into a dual gland that has both exocrine and endocrine functions begins when
    A.insulin is produced and bathes stem cells.
    B. a transcription factor stimulates progenitor cells to give rise to exocrine or endocrine cells.
    C. a globin gene duplicates and gives rise to alpha and beta globin genes.
    D. progenitor cells become stem cells.

Bloom’s Level: 02. Understand
Learning Outcome: 11.02 Explain how globin chain switching, development of organs, and the types of proteins cells make over time illustrate gene expression.
Section: 11.01
Topic: Epigenetics