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Genetics And Genomics for Nursing, 1st Edition Carole A. Kenne – Test Bank

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  • ISBN-10 ‏ : ‎ 0132174073
  • ISBN-13 ‏ : ‎ 978-0132174077

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Genetics And Genomics for Nursing, 1st Edition Carole A. Kenne – Test Bank

Kenner Genetics and Genomics for Nursing, 1/E
Chapter 7
Question 1
Type: MCSA
A client being treated for cancer is offended because she overheard a nurse say that the client had “wild-type genes.” How should the nurse respond to calm this client?
1. “Wild-type genes are a type of gene that is stronger than normal.”
2. “The nurse was describing your resilience in fighting your illness so effectively.”
3. “The nurse was discussing a type of gene we are seeing in clients treated for cancer.”
4. “Wild-type genes are those that are normal and have not been affected by any mutation.”
Correct Answer: 4
Rationale 1: Wild-type genes are not stronger-than-normal genes.
Rationale 2: The term wild-type genes does not refer to resilience.
Rationale 3: Wild-type genes are not caused by cancer treatments.
Rationale 4: Wild-type genes are those found in the common phenotype of a population.
Global Rationale:

Cognitive Level: Applying
Client Need: Physiological Integrity
Client Need Sub: Physiological Adaptation
Nursing/Integrated Concepts: Nursing Process: Implementation
Learning Outcome: 7-1: Describe Mendelian patterns of inheritance that contribute to inherited disorders.

Question 2
Type: MCMA
A client is diagnosed with a single-gene disorder on a non–sex chromosome. How would the nurse describe this disorder?
Standard Text: Select all that apply.
1. X-linked
2. Y-linked
3. Monogenic
4. Dominant
5. Autosomal
Correct Answer: 3,5
Rationale 1: X-linked disorders are associated with a sex chromosome.
Rationale 2: Y-linked disorders are associated with a sex chromosome.
Rationale 3: A single-gene disorder arises from a single defective gene; hence the term monogenic.
Rationale 4: The disorder may or may not be dominant.
Rationale 5: If the defective gene is not on a sex chromosome, it is termed autosomal.
Global Rationale:

Cognitive Level: Applying
Client Need: Physiological Integrity
Client Need Sub: Physiological Adaptation
Nursing/Integrated Concepts: Nursing Process: Implementation
Learning Outcome: 7-1: Describe Mendelian patterns of inheritance that contribute to inherited disorders.

Question 3
Type: MCMA
A client has been diagnosed with an autosomal recessive disorder that developed in middle adulthood. No other people in his family have manifested the disorder. The client asks the nurse why he is affected and if his children are at risk. What would the nurse consider when formulating a reply?

Note: Credit will be given only if all correct choices and no incorrect choices are selected.
Standard Text: Select all that apply.
1. The client’s mother is a carrier of the disorder.
2. The odds are high that at least one of the client’s four younger siblings either is a carrier for the disease or will develop it in later life.
3. The client’s father is a carrier for the disorder.
4. Because the disorder is recessive, the client’s children have a 25% chance of having inherited it.
5. All of the client’s children are at least carriers of the disorder.
Correct Answer: 1,2,3,5
Rationale 1: For the client to inherit an autosomal recessive disorder, his mother must have the disorder or be a carrier for it.
Rationale 2: Each sibling has a 50% chance of being a carrier and a 25% chance of developing the disease.
Rationale 3: For the client to inherit an autosomal recessive disorder, his father must have the disorder or be a carrier for it.
Rationale 4: The client’s children have a 50% chance of being affected.
Rationale 5: As this client has manifested the disorder, it is clear he inherited two recessive genes. The father must contribute one gene to each child, so it must be a recessive gene, making the children carriers. If the children’s mother also has the disorder or is a carrier, the children’s chances of developing the disorder are higher.
Global Rationale:

Cognitive Level: Analyzing
Client Need: Physiological Integrity
Client Need Sub: Physiological Adaptation
Nursing/Integrated Concepts: Nursing Process: Planning
Learning Outcome: 7-2: Describe the major characteristics of single gene Mendelian autosomal recessive disorders.

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